Substrate: Tyrosine-protein kinase Lyn (Tyr protein kinase family)
Seq-ID: P07948 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15243   SHC1_HUMAN
MINT-15994   HNRPK_RAT
MINT-16347   CBL_HUMAN
MINT-17535   KHDR1_HUMAN
MINT-17602   FAK1_HUMAN
MINT-48486   M3K3_HUMAN
MINT-50926   CIP4_HUMAN
MINT-61343   HCLS1_HUMAN
MINT-62784   CSK2B_HUMAN
MINT-2792057   PAK2_HUMAN
MINT-2792372   ADA15_HUMAN
MINT-7384444   ITB3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor signaling protein tyrosine kinase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
protein binding		 plasma membrane,
cytosol,
Golgi apparatus,
nucleus,
perinuclear region of cytoplasm,
membrane raft		 positive regulation of cell proliferation,
response to hormone stimulus,
positive regulation of cellular component movement,
positive regulation of stress-activated protein kinase signaling cascade,
erythrocyte differentiation,
positive regulation of tyrosine phosphorylation of STAT protein,
interspecies interaction between organisms,
response to DNA damage stimulus,
peptidyl-tyrosine phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 13 CIKSKGKDSLSDDGVDLKTQP - 17192257
HTP
0.23
 - -
0.60
 - medium
S 13 CIKSKGKDSLSDDGVDLKTQP - 18088087
HTP
0.23
 - -
0.60
 - medium
Y 193 YKIRSLDNGGYYISPRITFPC - 16497976
HTP
0.72
 - SH2
0.12
 - medium
Y 193 YKIRSLDNGGYYISPRITFPC - 18083107
HTP
0.72
 - SH2
0.12
 - medium
Y 194 KIRSLDNGGYYISPRITFPCI - 18083107
HTP
1.00
 - SH2
0.12
 - medium
Y 306 TLQHDKLVRLYAVVTREEPIY - 18083107
HTP
0.69
 - TyrKc
0.10
 - medium
Y 397 GLARVIEDNEYTAREGAKFPI Lyn 8530369
LTP
0.86
 - TyrKc
0.16
 - medium
Y 397 GLARVIEDNEYTAREGAKFPI - 17081983
HTP
0.86
 - TyrKc
0.16
 - medium
Y 397 GLARVIEDNEYTAREGAKFPI - 18088087
HTP
0.86
 - TyrKc
0.16
 - medium
Y 397 GLARVIEDNEYTAREGAKFPI - 18083107
HTP
0.86
 - TyrKc
0.16
 - medium
Y 473 PRVENCPDELYDIMKMCWKEK - 18083107
HTP
1.00
 - TyrKc
0.17
 - medium
Y 508 DDFYTATEGQYQQQP       Csk 9171348
LTP
0.99
 MOD_TYR_CSK
 - -
0.41
 - medium
Y 508 DDFYTATEGQYQQQP       - 18083107
HTP
0.99
 MOD_TYR_CSK
 - -
0.41
 - medium

Substrate: Tyrosine-protein kinase Lyn (Tyr protein kinase family)
Seq-ID: P25911 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-58750   SKAP2_MOUSE
MINT-58751   FYB_MOUSE
MINT-58757   SRC8_MOUSE
MINT-58758   HCLS1_MOUSE
MINT-58759   BCAR1_MOUSE
MINT-58760   EFS_MOUSE
MINT-58761   IRS2_MOUSE
MINT-58762   DBNL_MOUSE
MINT-58763   DOK2_MOUSE
MINT-7137863   CRKL_HUMAN
MINT-7214337   PLCG2_MOUSE
MINT-7214388   P85A_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
erythropoietin receptor binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 Golgi apparatus,
nucleus,
perinuclear region of cytoplasm		 intracellular signaling pathway,
B cell receptor signaling pathway,
hemoglobin biosynthetic process,
signal transduction,
neuron projection development,
erythrocyte differentiation,
positive regulation of tyrosine phosphorylation of STAT protein,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 KDNLNDDEVDSKTQPVRNTDR - 19144319
HTP
0.15
 - -
0.75
 --
Y 397 GLARVIEDNEYTAREGAKFPI Lyn 10415030
LTP
0.88
 - TyrKc
0.16
 --
Y 508 DDFYTATEGQYQQQP       Csk 10415030
LTP
0.99
 MOD_TYR_CSK
 - -
0.42
 --

Substrate: Tyrosine-protein kinase Lyn (Tyr protein kinase family)
Seq-ID: P25911-2 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
erythropoietin receptor binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 Golgi apparatus,
nucleus,
perinuclear region of cytoplasm		 intracellular signaling pathway,
B cell receptor signaling pathway,
hemoglobin biosynthetic process,
signal transduction,
neuron projection development,
erythrocyte differentiation,
positive regulation of tyrosine phosphorylation of STAT protein,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 KDNLNDDEVDSKTQPVPEFHL - 19144319
HTP
0.08
 - -
0.60
 --
Y 376 GLARVIEDNEYTAREGAKFPI - 19144319
HTP
0.89
 - TyrKc
0.16
 --
Y 487 DDFYTATEGQYQQQP       - 19144319
HTP
0.99
 - -
0.42
 --

Valid HTML 4.01 Transitional